Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system

Jing Chen, Jessica B. Buchanan, Nathan L. Sparkman, Jonathan P. Godbout, Gregory G. Freund, Rodney W. Johnson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)301-311
Number of pages11
JournalBrain, Behavior, and Immunity
Issue number3
StatePublished - Mar 2008
Externally publishedYes

ASJC Scopus Subject Areas

  • Immunology
  • Endocrine and Autonomic Systems
  • Behavioral Neuroscience


  • Aging
  • Hippocampus
  • Interleukin-1
  • Laser capture microdissection
  • Lipopolysaccharide
  • Working memory

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