Palladium and Iron Cocatalyzed Aerobic Alkene Aminoboration

Brittany L. Gay, Ya Nong Wang, Shreeja Bhatt, Anika Tarasewicz, Daniel J. Cooke, E. Grace Milem, Bufan Zhang, J. Brannon Gary, Michael L. Neidig, Kami L. Hull

Research output: Contribution to journalArticlepeer-review


Aminoboration of simple alkenes with nitrogen nucleophiles is a challenge in synthetic chemistry. Although palladium can catalyze this transformation, it faces stability issues. A new method using a combination of palladium and iron as cocatalysts has been developed to address this. The iron cocatalyst plays a key role in achieving the desired reaction and in regenerating the palladium catalyst. This method has been successfully demonstrated on various alkenes and nitrogen nucleophiles.
Original languageEnglish
Pages (from-to)18939-18947
Number of pages9
JournalJournal of the American Chemical Society
Issue number34
StatePublished - Aug 30 2023

ASJC Scopus Subject Areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this